Abstract: Objectives---In order to decrease the incidence of End Stage Renal Disease (ESRD) in Taiwan, our government has incorporated CKD prevention and health care into the important administrative task since 2003. We hope to enhance the CKD health education, to promote screening of CKD, to provide the counseling service of CKD prevention and control, and to implement the health management on CKD patients. Methods---To correspond approximately with the concepts of primary, secondary and tertiary prevention, we implemented health education, early detection, and health management. Results---Multi-sector including government, professional society, medical care facilities, and community collaborate on CKD health promotion program. Primary prevention－ Various media (television, radio, newspapers, internet) are being used to conduct a series of health education. Awareness activities in response to "World Kidney Day" were implemented. Secondary prevention－ Integrated community screenings for chronic diseases in adults and elderly were implemented, and followed by community health management programs. Tertiary prevention－ By setting up health promotion institutions to implement the health management on CKD patients. There are medical professional teams consisting of doctors, nurses, dieticians, and other medical professionals to care patients in different medical facilities. A CKD registration system was established, which encompassed configuration of the registration platform, establishment of the registration standard flow and construction of the registration information quality mechanism. Between 2005 and 2008, a total of 134 medical institutions participated in online registration and more than 36,399 cases completed registration. Furthermore, an integrated research of CKD prevention and control has been underway, which contains local epidemiology, therapeutic and diagnostic techniques, health care, and medical payments. Conclusions---The public health education and the further education of medical professional play an important role in conveying correct knowledge. Integrating multi -sectoral cooperation and settings can approach to CKD health promotion.With the interdisciplinary health management, CKD patients may receive better care.